yo i just did cocaine for the first time ever last night

Discussion in 'Overtime: Off-Topic Discussion' started by kenchilla, Nov 28, 2010.

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  1. A.K. Rowling

    A.K. Rowling harry shotta

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    weed slightly temporarily inhibits serotonin uptake in the brain, leading to
    random and unconnected thoughts and impaired memory & reaction time
    while high. It also dilates your lungs, increases heart & breathing rates
    and can irritate your respiratory system.

    cocaine will actiually create new synapses in your brain that
    lack pain receptors and will only function in the presence of the drug.
    When you're not using you feel depressed, lethargic & unwell. It slowly
    breaks down your nervous, cardiovascular, respiratory & immune system,
    and does so slowly overtime so that lifelong addiction is very plausible.
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  2. Kaysersoze

    Kaysersoze New Member

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    mookie, i admire people who actually do research before speaking out of their asses....respect homey
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  3. A.K. Rowling

    A.K. Rowling harry shotta

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    youre an idiot

    Tetrahydrocannabinol (pronounced /ˌtɛtrəˌhaɪdrɵkəˈnæbɨnɒl/ tet-rə-HYE-drə-kə-NAB-i-nol) (THC), also known as delta-9-tetrahydrocannabinol (Δ9-THC), Δ1-THC (using an older chemical nomenclature), or dronabinol, is the main psychoactive substance found in the cannabis plant.

    It was first isolated by Yechiel Gaoni and Raphael Mechoulam from the Weizmann Institute of Science in Rehovot, Israel, in 1964.[4][5][6] In pure form, it is a glassy solid when cold, and becomes viscous and sticky if warmed. An aromatic terpenoid, THC has a very low solubility in water, but good solubility in most organic solvents.

    Like most pharmacologically-active secondary metabolites of plants, THC in cannabis is assumed to be involved in self-defense, perhaps against herbivores.[7] THC also possesses high UV-B (280-315 nm) absorption properties, which, it has been speculated, could protect the plant from harmful UV radiation exposure.[8][9][10]

    [​IMG]

    The pharmacological actions of THC result from its binding to the cannabinoid receptor CB1, located mainly in the central nervous system, and the CB2 receptor, mainly present in cells of the immune system. It acts as a partial agonist on both receptors, i.e., it activates them but not to their full extent. The psychoactive effects of THC are mediated by its activation of the CB1 receptor, which is the most abundant G protein-coupled receptor in the brain.

    The presence of these specialized receptors in the brain implied to researchers that endogenous cannabinoids are manufactured by the body, so the search began for a substance normally manufactured in the brain that binds to these receptors, the so-called natural ligand or agonist, leading to the eventual discovery of anandamide, 2-arachidonyl glyceride (2-AG), and other related compounds known as endocannabinoids. This is similar to the story of the discovery of endogenous opiates (endorphins, enkephalins, and dynorphin), after the realization that morphine and other opiates bind to specific receptors in the brain. In addition, it has been shown that cannabinoids, through an unknown mechanism, activate endogenous opioid pathways involving the μ1 opioid receptor, precipitating a dopamine release in the nucleus accumbens. The effects of the drug can be suppressed by the CB1 cannabinoid receptor antagonist rimonabant (SR141716A) as well as opioid receptor antagonists (opioid blockers) naloxone and naloxonazine.[12]
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  4. J_Logic

    J_Logic New Member

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    I just like to smoke crack everyday. It doesnt make me a crackhead
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  5. TWAMP$iN

    TWAMP$iN proper weaponry

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    i'm not getting into this argument.




    you muthafuckas pop Tylenol and then turn around and say weed is a drug.




    it may be a "drug" but it's nowhere near the rest of the shit out there.
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  6. TWAMP$iN

    TWAMP$iN proper weaponry

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    go post some more stuff off wikipedia.





    people believe whatever is told to them.



    it's a damn shame.
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  7. FunGus3

    FunGus3 New Member

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    I fux wid dat fishscale. Shit will amke you drink like a champ.
    Posted via Mobile Device
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  8. You are mad

    You are mad Ur so angry

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    I like how kids can wiki their way into some pseudo-intellectual bullshit.


    The bottom line is weed is a harmless drug, and coke is not. GG
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  9. A.K. Rowling

    A.K. Rowling harry shotta

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  10. A.K. Rowling

    A.K. Rowling harry shotta

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    wiki is a good tool
    youre pretty dumb to deny that tbh.
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  11. roc55555

    roc55555 Well-Known Member

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    Drugs suck. I'd rather drink an ice cold beer any day of the week!
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  12. TWAMP$iN

    TWAMP$iN proper weaponry

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    arrogance like this isn't even worth a reply more than this here.
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  13. A.K. Rowling

    A.K. Rowling harry shotta

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    say it again, maybe I'll believe you.
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  14. Chill Status

    Chill Status Member

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    Tell that to Rick James. It ruined his career, ruined his voice, had his pockets on slim fast and he's not even on this planet anymore.

    PLUS: Cocaine use can give you a deviated septum in the nasal passage. The coke eats away at it and you will start having uncontrollable nose bleeds unless surgery is done. Which adds to the spendage of more money.
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  15. ManiphestDestNE

    ManiphestDestNE Well-Known Member

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    alcohol is one of the worst drugs EVER! weed n shrooms r where its at
    most coke is garbage n if u do pills, crack, heroin.... kill ya self
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  16. kenchilla

    kenchilla New Member

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    word tho, coke is a "hard drug" but it was fun as hell tho lol. the comedown sucks but i mean. we only live once
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  17. kenchilla

    kenchilla New Member

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    nigga, do you know how expensive that shit is? i swore id never do that shit and i ended meeting a couple chicks at the bar last night who would share if they had a place to do it at. so they gave me about 6 lines of some fire ass ye. i am still a bit fucked up i believe. i mean i wasnt trying to touch that shit and get addicted. prob a one time deal for me tbh
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  18. wickedness

    wickedness Dopeness

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    weed over a cold one. word
    Posted via Mobile Device
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  19. Kaysersoze

    Kaysersoze New Member

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    really? ur argument is that there's a conspiracy theory out there "telling" us weed has negative effects on the body? where do you get ur info? fuckin high times magazine?

    don't drink milk..it makes ur children sick...so does the MMR..gives u autism...flu shot gives u dystonia
    they always tell you to eat your vegetables...BECAUSE THEY'RE POSIONED


    hahah i'mma let mookie handle the rest of this..homeboy is schooled on the art of the ganja
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  20. You are mad

    You are mad Ur so angry

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    There are actually negative effects from too much calcium, just saying :p
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